Combogesic® – First Acetaminophen + Ibuprofen Combination Tablet – Now Available for Canadians with Acute Pain

New treatment option offers a clinically proven 3.3:1 acetaminophen to ibuprofen ratio 

MISSISSAUGA, Ontario, March 16, 2021 – BioSyent Inc. is now available in many pharmacies across Canada. Combogesic is used  for the short-term management of mild to moderate acute pain and the reduction of fever in adults over 18 years. Combogesic is the first Health Canada approved combination analgesic that provides the double action of two well-known and effective medicines, acetaminophen and ibuprofen, in one – patented formulation – tablet. 

“The goal of post-surgical acute pain management is to reduce the frequency and severity of pain and prevent an acute pain from becoming chronic.  In addition, the prevention of complications, the ability to speed-up healing, and minimizing potential side effects caused by analgesics are critical,” said Dr. Hance Clarke, Medical Director of The Pain Research Unit at Toronto General Hospital.  “In March 2020, experts published a clinical consensus statement for acute pain management following elective surgery which recommends acetaminophen and ibuprofen as the norm in postoperative prescribing.  Being able to recommend acetaminophen and ibuprofen at a specific three-to-one dose via Combogesic  might be a convenient, effective acute pain management option and lead to a reduced pill burden.”

The efficacy of Combogesic is based on its clinically proven ratio – one tablet contains 325 mg of acetaminophen and 97.5 mg of ibuprofen. With its unique 3.3:1 ratio, Combogesic is a faster and more effective pain reliever than either acetaminophen or ibuprofen alone in the same doses (78% more effective than acetaminophen and 36% more effective than ibuprofen)*.

“A novel combination of two popular non-prescription analgesics – ibuprofen and acetaminophen – Combogesic provides clinicians with an additional therapeutic option for achieving multimodal analgesia for mild to moderate pain management in adults without compromising the well-established safety profile of either active constituent,” said Dr. Nardine Nakhla, a community pharmacist and clinical lecturer at the University of Waterloo School of Pharmacy.

“Combogesic is a new and effective opioid-free treatment to support Canadian healthcare providers in the acute pain management for those patients in need. We look forward to helping patients who are looking for short term pain relief”, said Dr. Navid Ashrafi, Director, Medical & Regulatory Affairs, BioSyent Pharma. 

Combogesic is available behind the pharmacy counter without a prescription or by ordering online. You can find more information about Combogesic® at

About the author

Asia Metro Editor

Surjit Singh Flora
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